3-Fluoropropyl iodide
1-Fluoro-3-iodopropane
CAS: 462-40-8
Molecular Formula: C3H6FI
3-Fluoropropyl iodide - Names and Identifiers
3-Fluoropropyl iodide - Physico-chemical Properties
| Molecular Formula | C3H6FI |
| Molar Mass | 187.98 |
| Density | 1.837±0.06 g/cm3(Predicted) |
| Boling Point | 68-69/95mm |
| Flash Point | 33.8°C |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Appearance | Oil |
| Color | Colourless |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Stability | Volatile |
| Refractive Index | 1.4955 |
3-Fluoropropyl iodide - Risk and Safety
| Hazard Symbols | T - Toxic |
| Hazard Note | Toxic |
3-Fluoropropyl iodide - Introduction
1-Fluoro-3-iodopropane, chemical formula C3H6FI, is an organic compound. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
1-Fluoro-3-iodopropane is a colorless liquid with a pungent odor at room temperature. It has a density of 2.03 g/mL, a melting point of -35°C, and a boiling point of 118°C. The compound is hardly soluble in water but soluble in organic solvents such as alcohols and ethers.
Use:
1-Fluoro-3-iodopropane has a wide range of applications in the field of organic synthesis. It can be used as an important intermediate for the synthesis of chemicals and drugs. Its donor-acceptor nature makes it a useful precursor for catalysts and ligands. In addition, it can also be used in the synthesis of organic phosphorus compounds, amino ketones and other fluorine-containing compounds.
Preparation Method:
1-Fluoro-3-iodopropane can be prepared by reacting iodopropane with hydrogen fluoride. First, iodopropane is reacted with hydrogen fluoride at a low temperature to produce 1-fluoro-2-iodopropane, which is then reacted again with hydrogen fluoride to give 1-Fluoro-3-iodopropane.
Safety Information:
1-Fluoro-3-iodopropane is potentially dangerous. Contact with skin, eyes or inhalation of its vapor may cause irritation and discomfort, so appropriate safety measures should be taken during operation. Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water. In addition, the compound should be kept away from fire and high temperatures.
Summary:
1-Fluoro-3-iodopropane is an organic compound with a wide range of applications. In organic synthesis, it is an important intermediate that can be used in the synthesis of chemicals and drugs. The preparation of this compound requires the reaction of iodopropane with hydrogen fluoride. Pay attention to safety during operation and avoid contact with skin and eyes.
Nature:
1-Fluoro-3-iodopropane is a colorless liquid with a pungent odor at room temperature. It has a density of 2.03 g/mL, a melting point of -35°C, and a boiling point of 118°C. The compound is hardly soluble in water but soluble in organic solvents such as alcohols and ethers.
Use:
1-Fluoro-3-iodopropane has a wide range of applications in the field of organic synthesis. It can be used as an important intermediate for the synthesis of chemicals and drugs. Its donor-acceptor nature makes it a useful precursor for catalysts and ligands. In addition, it can also be used in the synthesis of organic phosphorus compounds, amino ketones and other fluorine-containing compounds.
Preparation Method:
1-Fluoro-3-iodopropane can be prepared by reacting iodopropane with hydrogen fluoride. First, iodopropane is reacted with hydrogen fluoride at a low temperature to produce 1-fluoro-2-iodopropane, which is then reacted again with hydrogen fluoride to give 1-Fluoro-3-iodopropane.
Safety Information:
1-Fluoro-3-iodopropane is potentially dangerous. Contact with skin, eyes or inhalation of its vapor may cause irritation and discomfort, so appropriate safety measures should be taken during operation. Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water. In addition, the compound should be kept away from fire and high temperatures.
Summary:
1-Fluoro-3-iodopropane is an organic compound with a wide range of applications. In organic synthesis, it is an important intermediate that can be used in the synthesis of chemicals and drugs. The preparation of this compound requires the reaction of iodopropane with hydrogen fluoride. Pay attention to safety during operation and avoid contact with skin and eyes.
Last Update：2024-04-09 21:32:41
